Publications
#Equal contribution; *Corresponding author
18. T.J. Trinklein#, S. Okyem#, S. S. Rubakhin, J.V. Sweedler*, Spatially mapping neuropeptides and their isomers by MALDI - trapped ion mobility MS, In Preparation
17. T.J. Trinklein, S.S. Rubakhin, S. Okyem, M. Asadian, S.W. Croslow, K.R. Sabitha, O. Lazarov*, F. Lam*, J.V. Sweedler*, Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in an Alzheimer’s disease mouse model, Under review
16. Y.R. Xie, D.C. Castro, S.S. Rubakhin, T.J. Trinklein, J.V. Sweedler*, F. Lam*, Multiscale biochemical mapping of the brain through deep-learning-enhanced high-throughput mass spectrometry, Nature Methods, 2024, 1-10.
15. T.J. Trinklein#, S.W. Croslow#, J.V. Sweedler*, Advances in multimodal mass spectrometry for single-cell analysis and image enhancement, FEBS Letters, 2024, 1-10.
14. T.J. Trinklein#, C.N. Cain#, G.S. Ochoa, S. Schöneich, L. Mikaliunaite, and R.E. Synovec*, Recent advances in GC×GC and chemometrics to address emerging challenges in non-targeted analysis, Analytical Chemistry, 95, 2023, 264-286.
13. L. Mikaliunaite, T.J. Trinklein, G.S. Ochoa, P.E. Sudol, D.S. Bell, R.E. Synovec*, Valve-based comprehensive two-dimensional gas chromatography with quadrupole mass spectrometry detection using a porous layer open tubular column in the first dimension, Journal of Chromatrography Open, 3, 2023, 100076.
12. T.J. Trinklein#, R.C. Halvorsen#, C.G. Warren, R.D. Rogan, R.E. Synovec*, Optimizing column-to-column retention time alignment in high-speed gas chromatography by combining retention time locking and correlation optimized warping, Talanta, 254, 2023, 124173
11. T.J. Trinklein, R.E. Synovec*, Simulating comprehensive two-dimensional gas chromatography mass spectrometry data with realistic run-to-run shifting to evaluate the robustness of tile-based Fisher ratio analysis, Journal of Chromatography A, 1677, 2022, 463321
10. T.J. Trinklein, J. Jiang, R.E. Synovec*, Profiling olefins in gasoline by bromination using GC×GC-TOFMS followed by discovery-based comparative analysis, Analytical Chemistry, 94, 2022, 9407-9414
9. C.N. Cain, T.J. Trinklein, G.S. Ochoa, R.E. Synovec*, Tile-based pairwise analysis of GC×GC-TOFMS data to facilitate analyte discovery and mass spectrum purification, Analytical Chemistry, 94, 2022, 5658-5666
8. G.S. Ochoa, P.E. Sudol, T.J. Trinklein, R.E. Synovec*, Class comparison enabled mass spectrum purification for comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry, Talanta, 236, 2021, 122844
7. T.J. Trinklein, C.G. Warren, R.E. Synovec*, Determination of the signal-to-noise ratio enhancement in comprehensive three-dimensional gas chromatography, Analytical Chemistry, 93, 2021, 8526-8535
6. T.J. Trinklein, M. Thapa, L.A. Lanphere, J.A. Frost, S.M. Koresch, J.H. Aldstadt*, Sequential injection analysis coupled to on-line benchtop proton NMR: Method development and application to the determination of synthetic cathinones in seized drug sampels, Talanta, 231, 2021, 122355
5. T.J. Trinklein, S. Schöneich, P.E. Sudol, D.V. Gough, R.E. Synovec*, Total-transfer comprehensive three-dimensional gas chromatography with time-of-flight mass spectrometry, Journal of Chromatogaphy A, 1634, 2020, 461654
4. T. J. Trinklein#, S. Schöneich#, C.G. Warren, R.E. Synovec*, A systematic investigation of comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry with dynamic pressure gradient modulation for high peak capacity separations, Analytica Chimica Acta, 1131, 2020, 115-124
3. T.J. Trinklein, S.E. Prebihalo, C.G. Warren, G.S. Ochoa, R.E. Synovec*, Discovery-based analysis and quantification for comprehensive three-dimensional gas chromatography flame ionization detection, Journal of Chromatography A 1623, 2020, 461190
2. S. Schöneich, D.V. Gough, T. J. Trinklein, R.E. Synovec*, Dynamic pressure gradient modulation for comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry detection, Journal of Chromatography A 1620, 2020, 460982
1. T.J. Trinklein, D.V. Gough, C.G. Warren, G.S. Ochoa, R.E. Synovec*, Dynamic pressure gradient modulation for comprehensive two-dimensional gas chromatography, Journal of Chromatography A 1609, 2020, 460488
Book Chapters
2. Chemometric Analysis of Comprehensive Two-Dimensional Separations - Advances in Chromatography C.N. Cain, T. J. Trinklein, G.S. Ochoa, S. Schoneich, Sarah C. Rutan, R.E. Synovec (editor: Peter W. Carr) CRC Press, 29th December 2022, ISBN: 9781003330080
1. Chapter 20: Data analysis methods in chromatography - Gas Chromatography, 2nd Edition K.J. Pierce, T.J. Trinklein, J.S. Nadea, R.E. Synovec (editor: Colin F. Poole).
Elsevier, 15th April 2021, ISBN: 9780128206751